Clinical Research Studies

RTOG 1005

A randomized phase III trial looking at shortening the treatments for select women with breast cancer.
http://www.rtog.org/ClinicalTrials/ProtocolTable/StudyDetails.aspx?study=1005

The NCI is scientifically looking into ways to reduce the cost and inconvenience of cancer care- this is one such trial.


RTOG 0413/NSABP B-39

A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) versus Partial Breast Irradiation (PBI) for Women with Stage 0, I, or II Breast Cancer

RTOG 0974/NSABP B-43

A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER-2 Positive Ductal Carcinoma In Situ Resected by Lumpectomy.

RTOG 0524

A Phase I/II Trial of a Combination of Paclitaxel and Trastuzumab With Daily Irradiation or Paclitaxel alone With Daily Irradiation Following Transurethral Surgery for Non-Cystectomy Candidates With Muscle-Invasive Bladder

RTOG 0933

A Phase II Trial of Hippocampal Avoidance During Whole Brain Radiotherapy for Brain Metastases--RTOG CCOP Study

RTOG 0436

A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients With Esophageal Cancer Who Are Treated Without Surgery

RTOG 0848

A Phase III Trial Evaluating both Erlotinib And Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma

RTOG 1010

A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of Her2-Overexpressing Esophageal Adenocarcinoma

RTOG 0920

A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer

RTOG 1016

Phase III Trial of Radiotherapy Plus Cetuximab Versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer

RTOG 1012

Phase II Randomized Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy Induced Esophagitis-Related Pain During the Treatment of Lung Cancer - RTOG CCOP Study (open to U.S. sites only)

RTOG 1005

Evaluate the relative efficacy of 4 times a day consumption of liquid or lozenge Manuka honey to delay or prevent radiation esophagitis-related pain (during combined chemotherapy and radiation therapy for lung cnancer) as compared to standard supportive treatment, as measured at week 4 by Numerical Rating Pain Scale (NRPS) for pain upon swallowing
http://www.rtog.org/ClinicalTrials/ProtocolTable/StudyDetails.aspx?study=1012

RTOG 0538

CALGB 30610/Endorsed Study: Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer Also Receiving Cisplatin and Etoposide

RTOG 0813

Seamless Phase I/II Study of Stereotactic Lung Radiotherapy (SBRT) for Early Stage, Centrally Located, Non-Small Cell Lung Cancer (NSCLC) in Medically Inoperable Patients

RTOG 0937

Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone To Prophylactic Cranial Irradiation And Consolidative Extra-Cranial Irradiation For Extensive Disease Small Cell Lung Cancer (ED-SCLC)

Jefferson/Genentech #OSI4327s

A Phase II Study of Erlotinib (Tarceva) and hypofractionated thoracic radiotherapy for patients with advanced or inoperable non-small lung cancer

RTOG 0938

Protocol Information A Randomized Phase II Trial Of Hypofractionated Radiotherapy For Favorable Risk Prostate Cancer-RTOG CCOP Study.

This protocol examines the effect of 5 or 12 treatments of prostate radiotherapy, by giving more dose per day, as an alternative to standard fractionation treatments which usually take between 40 and 45 treatments.


RTOG 0526

A Prospective Phase II Trial of Transperineal Ultrasound-Guided Brachytherapy for Locally Recurrent Prostate Adenocarcinoma Following External Beam Radiotherapy

RTOG 0534

A Phase III Trial of Short Term Androgen Deprivation With Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients With a Rising PSA After Radical Prostatectomy

RTOG 0622

A Phase II Trial of Samarium 153 Followed By Salvage Prostatic Fossa 3D-CRT or IMRT Irradiation In High-Risk, Clinically Non-Metastatic Prostate Cancer after Radical Prostatectomy

RTOG 0815

A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy with or without Short-Term Androgen Deprivation Therapy for Patients with Intermediate-Risk Prostate Cancer

RTOG 0924

Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial